D-(-)-Ribose CAS 50-69-1 Assay 97.0~102.0% Factory AJI97

Short Description:

Chemical Name: D-(-)-Ribose

CAS: 50-69-1

White Crystals or Crystalline Powder; Sweet Taste

Assay: 97.0%~102.0% (on Dried Basis) 

Production Capacity 1000 Tons per Year, AJI97 Standard

Contact: Dr. Alvin Huang     

Mobile/Wechat/WhatsApp: +86-15026746401  

E-Mail: alvin@ruifuchem.com   


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50-69-1 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of D-(-)-Ribose (CAS: 50-69-1) with high quality, meet the specification of AJI97, production capacity 1000 tons per year. Our products sell well in domestic and international market, trusted by customers. We can provide worldwide delivery, small and bulk quantities available. If you are interested in D-(-)-Ribose, Please contact: alvin@ruifuchem.com 

50-69-1 - Chemical Properties:

Chemical Name D-(-)-Ribose
Synonyms D-Ribose; Dextro-Ribose; Ribose; D-RIB
CAS Number 50-69-1
Stock Status In Stock, Production Capacity 1000 Tons per Year  
Molecular Formula C5H10O5
Molecular Weight 150.13
Melting Point 80.0℃~ 90.0℃
Density   1.6810
Sensitive Hygroscopic
Solubility Soluble in Water. Insoluble in Ether 
COA & MSDS Available
Origin of Product   Shanghai, China
Brand Ruifu Chemical

50-69-1 - Specifications:

Item Specifications Results
Description White Crystals or Crystalline Powder White Crystalline Powder 
State of Solution  ≥95.0% (Transmittance) 99.4%
Assay / Analysis Method 97.0%~102.0% (HPLC, on Dried Basis) 99.5% 
Melting Point 80.0℃~ 90.0℃ 86.2℃ 
Specific Rotation [α]D20 -19.0°~-21.0° (Dried Sample, C=4, H2O) -19.5° 
Loss on Drying ≤2.00% 0.09% 
Residue on Ignition (Sulfated) ≤0.20% 0.05% 
Heavy Metals (Pb) ≤10ppm <10ppm 
Arsenic (As2O3) ≤1ppm <1ppm  
Other Saccharide Chromatographically Not Detectable Complies 
Bacteria Count  ≤100cfu/g <10cfu/g 
Mould & Yeast ≤100cfu/g <10cfu/g
Escherichia Coli ≤10cfu/g Not Detected 
Salmonella Do Not Detected in 25g Not Detected 
Pathogenic Bacteria Negative Negative
Conclusion The product has been tested and complies with the AJI97 specifications 

50-69-1 - AJI97 Test Method:

D-(-)-Ribose (CAS: 50-69-1) AJI97 Test Method
D-(-)-Ribose, when dried, contains not less than 97.0 percent and not more than 102.0 percent of D-(-)-Ribose (C5H10O5).
Description: White crystals or crystalline powder, sweet taste
Solubility (H2O, g/100g): about 83 (25℃)
Specifications:
Specific Rotation [α]20/D: Dried sample, C=4, H2O
State of Solution (Transmittance): 0.5g in 10ml of H2O, spectrophotometer, 430nm, 10mm cell thickness.
Heavy Metals (Pb): 2.0g, (1), ref: 2.0ml of Pb Std. (0.01mg/ml)
Arsenic (As2O3): 1.0g, (5), ref: 2.0ml of As2O3 Std.
Other Saccharides: Chromatographically not detectable. Test sample: 10μg, A-4-a
Loss on Drying: In vacuum, at 60℃ for 3 hours
Residue on Ignition (Sulfated): AJI Test 13
Assay: Dried sample, 1.0g/500ml →10ml, 0.1mol/L Na2S2O3 1ml=1.877mg C5H10O5
pH: 1.0g in 10ml of H2O
Recommended storage limit and condition: Preseved tight containers at controlled room temperature (1 years).

50-69-1 - Package/Storage/Shipping:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with strong oxidizing agents.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.

50-69-1 - Advantages:

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50-69-1 - FAQ:

www.ruifuchem.com

50-69-1 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/38 - Irritating to eyes and skin.
Safety Description S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS VJ2275000
FLUKA BRAND F CODES 3-10
TSCA Yes
HS Code 2940009090

50-69-1 - Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of D-(-)-Ribose (CAS: 50-69-1) with high quality, is widely used as pharmaceutical raw materials, health products, food additives and so on.
1. D-(-)-Ribose is used as the most promising starting material for the first approved domestic oral drug Azfudine for COVID-19.
2. D-(-)-Ribose is a key pharmaceutical intermediate of many nucleotide drugs. Nucleic acid drugs are an important means of human treatment of viruses, tumors and AIDS. D-(-)-Ribose is an important intermediate of many nucleic acid drugs. D-(-)-Ribose is mainly used as a very basic source of metabolism of life. It is also used as a precursor for virazole, adenosine, thymidine, cytidine, fluoro-thymidine, 2-methyl adenosine, pyrromonazole toxina and adenosine methionine. It is further used in the synthesis of vitamin B2 (riboflavin), tetra-O-acetyl-ribose and nucleoside. It finds application as food additives and as supplement in cell culture.
3. In the field of medicine, D-(-)-Ribose is an important intermediate and starting material for a variety of nucleosides, anti-tumor and other drugs. Nearly 50% of the antiviral drugs in clinical use are nucleosides, such as Capecitabine, Ticagrelor and Remdesivir, which all use D-(-)-Ribose as the intermediate and starting material.
4. D-(-)-Ribose is used as the starting material for the so-called elixir NMN; D-(-)-Ribose is also used as a functional new beverage additive and a feed additive to promote the development of animal pups.
5. D-(-)-Ribose is a dietary supplement in the U.S. market and has been approved by the FDA as a novel food ingredient. When ingested more than 200mg/ (kg·h) ribose may cause diarrhea. Excessive intake can cause intestinal dehydration. A small number of people may experience mild symptoms such as nausea and dizziness, but most people have no adverse effects when the dosage is less than 15g/d. In addition, ribose has a short half-life, reaching its maximum value in about 30 minutes and being absorbed in about 120 minutes. Although ribose is an effective way to replenish ATP in muscles, exercise experts do not recommend it as an energy booster for healthy young people.
6. D-(-)-Ribose is a carbohydrate, or sugar, used by all living cells and is an essential component in living organisms for energy production. It has a sweet taste. D-(-)-Ribose is mainly used as a very basic source of metabolism of life. It finds application as food additives and as supplement in cell culture. D-Ribose (mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. 

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